The 2030 Agenda for Sustainable Development emphasizes the interconnectedness of global challenges and the need for cross-sectoral collaboration. However, there is limited guidance on how to integrate such approaches into national and sub-national planning. This paper aims to provide indicative approaches for working across sectors to address complex issues related to sustainable food and nutrition, agriculture, and natural resources. It offers insights on cross-sectoral coordination at the country level, identifies factors that facilitate it, and explores the role of multistakeholder collaboration in supporting coordination. Drawing on literature and country studies, the analysis focuses on initial conditions, enabling factors, governance arrangements, and processes for effective cross-sectoral coordination.